AGRANULOCYTOSIS -Causes, symptoms ,risk ,diagnosis and treatment

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                  AGRANULOCYTOSIS

  • Lack of granulocyte 
  • Absolute neutrophil count (less than 100 per microliter)
  • Rare condition
  • Suppressed immune system






CAUSES:

  • May be inherited or genetic
  • Drugs: Anti-thyroid ,Anti-psychotic ,antibiotic
  • Exposure to toxic substance such as ARSENIC ,MERCURY
  • Aplastic anemia

SYMPTOM:

  • Sore throat and mouth
  • Fever ,chill
  • Fatigue 
  • Headache
  • Sweating 
  • Swollen gland





RISK:

  • If left untreated result in sepsis
  • Male and female both at equal risk
  • Certain drug 





DIAGNOSIS:

  • Blood test
  • Neutrophil count less than 100 per microliter of blood
  • Bone marrow biopsy








TREATMENT:

  • Change of drug
  • Transfusion of granulocyte 



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