RAYNAUD DISEASE ?/RAYNAUD PHENOMENON?/DIFFERENCE BETWEEN PRIMARY AND SECONDARY RAYNAUD DISEASE
RAYNAUD DISEASE
INTRODUCTION:
Raynaud phenomenon:
- Vascular disease characterized by intermittent arteriolar vasospasm of the digits
- Etiology :Cold temperature /stress
- Features: Exaggerated vasoconstriction of digital arteries and arterioles
- Pain
- Pallor
- Cyanosis
- Hyperemia
- Symptoms present with characteristic changing of hands from white to blue to red
PRIMARY RAYNAUD PHENOMENON:
- Also known as RAYMAUD DISEASE
- Less severe than secondary
- Its seen in females
- Usually bilateral
- Occur :upper limb and normal peripheral pulses
- Etiology :abnormal sensitivity to cold that result in upper limb (hand ) arteriolar spasm
- Symptoms can be precipitated
- Observed by placing hands in cold water
DIFFERENCE BETWEEN RAYNAUD PHENOMENON AND SECONDARY RAYNAUD PHENOMENON
PRIMARY RAYNAUD PHENOMENON:
- Also known as Raynaud disease
- Less severe than secondary
- Vasospasm is not associated with ischemic injury or an underlying associated disease
- Sex:women
- Age: <30 years
- Involves all fingers symmetrically excluding thumbs
- No structural abnormality in the arterial wall (later in course thickening of intima present)
- No history of peripheral vascular disease or ischemic injury
- Anti nuclear antibody titre -normal or low (on indirect immunofluorescence)
- Nailfold capillaries normal
SECONDARY RAYNAUD PHENOMENON:
- Also known as Raynaud syndrome
- Very severe
- Associated with underlying disease (systemic sclerosis)
- Associated with vasospasm and concurrent ischemia
- Painful attack
- Asymmetric involvement of digits
- Torturous nail fold
- Digital necrosis
INVESTIGATION:
- Type is identified by angiogram of palm
- X-ray of the part of limb affected
TREATMENT :
- Treat the cause
- Avoid precipitating factor
- Small dose of aspirin (100 mg daily)
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