Prokinetic drug - METOCLOPRAMIDE /pharmacology notes

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                 PROKINETIC DRUGS

  • Drug that promote gastrointestinal transit and hasten gastric emptying

METACLOPRAMIDE:

  • They act by blocking D2 dopamine receptor in CTZ -ANTIEMETIC ACTION
  • Enhances acetylcholine release from cholinergic neuron in gut

ACTION:

GASTROINTESTINAL TRACT:

  • Forward movement of content in upper gastrointestinal tract 
  • Increased gastric emptying
  • Prevent reflux esophagitis





CENTRAL NERVOUS SYSTEM:

  • Speeds up gastric emptying

USES:

  • Antiemetic
  • Preanesthetic medication
  • In endoscopy

ADVERSE EFFECT:

  • Sedation
  • Gynecomastia
  • Diarrhoea






Note: Kindly do not consume medication without consulting a physician ,notes on our site is to provide notes for students only.

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