BACTERIAL INFECTION - SYPHILIS ( ETIOLOGY,TYPES IN DETAIL NOTES )
SYPHILIS SYPHILIS is a world wide chronic infection produced by treponema pallidum History :christopher columbus and his crew returns from the new world possibly carrying syphilis Global epidemiology:15-49 years old- 6 million new cases each year Incidence decreased after penicillin Male is to female ratio is 1 is to 1 Fetal ,neonatal deaths- 3,00,000 ETIOLOGY: Treponema pallidum :gram positive ,motile ,spirochete and is pathogenic to human ROUTE OF TRANSMISSION: Sexual contact Vertical transmission (mother to foetus) TYPES: 1)CONGENITAL 2)ACQUIRED : PRIMARY,SECONDARY,TERTIARY 1)CONGENITAL SYPHILIS : Transmitted to offspring only infected mother and not inherited Totally preventable Recognised if treatment with antibiotic is begun in infected pregnant women before 4 months of pregnancy STIGMATA OF CONGENITAL SYPHILIS: 1)Head: Frontal bossing 2)Nose:Saddle nose 3)Eyes:Interstitial keratitis 4)Oropharynx;HUTCHINSON'S TRIAD HYPOPLASIA OF INCISOR -screw driver shaped inci